Mamelodi Sundowns were handed a tough draw in the African Football League quarter-finals.
Simba SC, representing Tanzania, will face the Egyptian giants Al Ahly in the first leg of the quarter-final on October 20.
Al Ahly is a dominant force in African football with 11 CAF Champions League titles, while Simba is aiming for their first-ever semi-final appearance in the new AFL.
TP Mazembe, a five-time Champions League winner from DR Congo, will take on Tunisian cup specialists Esperance, on October 21.
Nigerian side Enyimba, the first Nigerian club to win the CAF Champions League in 2003 and 2004, will face Moroccan heavyweights Wydad Casablanca, who have three titles to their name.
The quarter-final matchups conclude with Petro du Luanda from Angola taking on 2016 Caf Champions League winners Mamelodi Sundowns. However, Petro’s participation is contingent on the outcome of an appeal they filed with the Angolan Football Association regarding a discipline matter.