Orlando Pirates will be without midfielder, Ndabayithethwa Ndlondlo, for the DStv Premiership clash against Mamelodi Sundowns.
The midfielder is ruled out of the clash through suspension after accumulating four yellow cards in domestic competition this season.
Olisa Ndah and Karim Kimvuidi are getting closer to their first involvement of the season after being unused substitutes in a previous match.
Vincent Pule has returned to full training after missing the early part of the season due to injury.
For Mamelodi Sundowns, first-team regulars Abdelmounaim Boutouil and Neo Maema may miss the match due to injuries they picked up in recent weeks.
Lebogang Maboe is also serving a two-match suspension for a red card he received in a previous league encounter against Polokwane City.
Both teams had CAF Champions League assignments over the past weekend, with Orlando Pirates losing Jwaneng Galaxy and Mamelodi Sundowns winning their respective match against Bumamuru.
Orlando Pirates have a perfect record at Orlando Stadium this season, winning all four of their home matches in the league.
In their encounters last season, Mamelodi Sundowns won both league matches 1-0, while Orlando Pirates won the away leg of their MTN8 semifinal match 3-0 after a goalless draw at Orlando Stadium.
The Buccaneers will be looking for their first league victory in this fixture since January 2020 when they won at home with a first-half goal from Gabadinho Mhango.
The match is scheduled to kick off at 19:30.